X-ray Induced Chromosomal Aberrations in <i>Hordeum</i>

An Analysis of X-Ray Induced Chromosomal Aberrations in Tradescantia.

HE cause and nature of chromosomal alterations has become an imT portant genetic problem since it has been shown that both mutation and speciation often are associated with structural alterations of the chromosomes (DOBZHANSKY 1937). The frequency of spontaneous structural changes is too low in most organisms to permit a statistical analysis of types or frequencies of alterations, although rece...

micronuclei versus chromosomal aberrations induced by x-ray in radiosensitive mammalian cells.

an experimental study was accomplished to compare estimation methods of ionizing radiations genotoxicity in mammalian cell cultures by means of two cytogenetic parameters with focus on aberrant cells characterized by multiple chromosomal damages.in vitro study was carried out on the genotoxicity of low-medium doses of 190 kv x-rays absorbed in chinese hamster ovary cell cultures. micronuclei an...

Propranolol induced chromosomal aberrations in Chinese hamster ovary cell line

Propranolol (PL), a non-selective beta-blocker, is a cardiovascular drug widely used to treat hypertension. The present study was concerned with assessing the cytogenetic effects of this drug on Chinese hamster ovary (CHO) cell line. MTT assay was then carried out to determine the cytotoxicity index (IC50) of the drug. The IC50 value of PL was 0.43±0.02 mM. To investigate the clastogenic effect...

Micronuclei versus Chromosomal Aberrations Induced by X-Ray in Radiosensitive Mammalian Cells

BACKGROUND An experimental study was accomplished to compare estimation methods of ionizing radiations genotoxicity in mammalian cell cultures by means of two cytogenetic parameters with focus on aberrant cells characterized by multiple chromosomal damages. METHODS In vitro study was carried out on the genotoxicity of low-medium doses of 190 kV X-rays absorbed in Chinese hamster ovary cell cu...

The Effect of Temperature on X-Ray Induced Chromosome Aberrations.